Payarmin Ingredients: Every Label Entry, Milligram Breakdown & Research

The full ingredient list, in label order

Payarmin's label lists 23 active entries. One is itemized: chromium, at 0.7 mcg per 1 mL serving. The other 22 sit in a single 200 mg proprietary blend, written in descending order by weight, which tells you their ranking but not their size. Below is every entry in the order the bottle prints it, grouped for reading, with what each is, what human research found and what that means for a product where the whole blend weighs 200 mg.

The right-hand column is the honest problem with this formula. Almost every entry is studied in hundreds of milligrams or grams. The whole blend is 200 mg per serving, 400 mg at the label maximum of two droppers, shared 22 ways.

Chromium picolinate: the only itemized active

Chromium (as chromium picolinate), 0.7 mcg

Essential trace mineral; picolinate is a well-absorbed salt

Chromium helps insulin pass its signal into cells. A genuine deficiency, mainly seen in people fed intravenously for long periods, causes glucose intolerance that reverses when chromium is replaced. Normal diets supply it through whole grains, broccoli, potatoes, meat and some spices^[1].

The research: Results in people who are not deficient are inconsistent. A review in Nutrition Reviews concluded the evidence for glycemic control in type 2 diabetes is limited^[2]; a meta-analysis found small falls in fasting glucose in some subgroups, at 200 to 1,000 mcg a day^[3]. In overweight adults, weight changed by about half a kilogram versus placebo^[4].

In Payarmin: 0.7 mcg per serving is 2% of the 35 mcg Daily Value and between 1/300 and 1/1,400 of trial doses. It will not change your chromium status in any meaningful way.

Gymnema: sweet taste and post-meal glucose

Gymnema Leaf Extract

Gymnema sylvestre, a woody climber from India and Africa

The leaves contain gymnemic acids, which temporarily occupy sweet-taste receptors so that sugar tastes flat for up to about an hour. Traditional Ayurvedic use for "madhumeha", sweet urine, gave it the name gurmar^[5].

The research: The classic trial gave 400 mg a day of a specific extract to 22 people with type 2 diabetes for 18 to 20 months, alongside their medicine, and reported lower glucose and A1C^[6]. A 2021 meta-analysis found lower fasting glucose, post-meal glucose and A1C, with low-certainty evidence from small studies^[7].

In Payarmin: Listed eighth of 22. Its amount is unknown but far below 400 mg. In a liquid that touches the tongue, the brief sweet-blocking effect is the most realistic benefit, for example before a dessert you want to skip.

Green tea and guarana: catechins and caffeine

Green Tea (Camellia sinensis) Leaf Extract + Guarana (Paullinia cupana) Seed Extract

Two caffeine-bearing plants; green tea adds catechins such as EGCG

Green tea catechins are antioxidants studied for metabolism and weight. Guarana seeds hold roughly twice the caffeine of coffee beans by weight. Together they make Payarmin a mildly "stimulating" product, the word the maker's own FAQ uses.

The research: A meta-analysis of 17 trials found green tea lowered fasting glucose and A1C slightly, without clear changes in insulin^[8]. Concentrated green tea extracts are a recognized, rare cause of liver injury^[9]; a United States Pharmacopeia review tied the risk to high EGCG doses, especially taken fasting^[10]. The FDA treats about 400 mg of caffeine a day as an amount not generally linked to problems in healthy adults^[11].

In Payarmin: Guarana is third and green tea seventh. With 200 mg of blend shared 22 ways, the caffeine is likely a few milligrams to perhaps a couple of dozen, but the label does not say. Caffeine-sensitive readers should take it early in the day.

African mango, coleus, capsicum and raspberry ketones

African Mango (Irvingia gabonensis) Seed, Coleus Forskohlii Root, Capsicum Annuum Fruit, Raspberry Ketones

The weight-management cluster

These four appear in many weight products. African mango seed is rich in soluble fiber; coleus supplies forskolin, which raises cellular cAMP; capsicum supplies capsaicin, which causes mild heat and a small rise in energy use; raspberry ketone is an aroma compound.

The research: African mango results come mainly from one research group in Cameroon: weight and glucose changes at 3.15 g of seed^[12] and at 150 mg twice daily of a branded extract^[13]. A systematic review called the trials small and poorly reported^[14]. Forskolin was studied at 250 mg of a 10% extract twice a day, with changes in body composition but not weight^[15]. Raspberry ketone has essentially no human trial data on its own.

In Payarmin: African mango is fourth, coleus ninth, capsicum tenth, raspberry ketones thirteenth. None can approach the doses studied.

Ginseng, eleuthero, astragalus and maca

Panax Ginseng Aerial Extract, Eleutherococcus Senticosus Root, Astragalus Root, Maca (Lepidium meyenii) Root

The adaptogen cluster

Adaptogens are plants said to improve resistance to stress and fatigue. Maca is a Peruvian root vegetable used for energy and libido^[19]; astragalus is a staple of traditional Chinese medicine^[20]; eleuthero is often called Siberian ginseng, though it is a different genus.

The research: Panax ginseng has the most glucose research: a meta-analysis found a modest fall in fasting glucose, usually from 1 to 3 g a day of root^[16], and the NCCIH summary calls evidence for most uses limited^[17]. In a controlled trial, American ginseng weakened warfarin's effect^[18]. Maca studies use 1.5 to 3 g a day.

In Payarmin: Maca is listed first, so it is likely the largest entry, perhaps tens of milligrams. Note that the label lists ginseng aerial extract, leaves and stems, while most glucose trials used the root, and the sales page calls it a root.

Grape seed and grapefruit

Grape (Vitis vinifera) Seed Extract, Grapefruit (Citrus paradisi) Fruit Extract

Polyphenol-rich fruit extracts

Grape seed extract is concentrated proanthocyanidins. Grapefruit fruit extract carries flavonoids such as naringin and, depending on the part used, furanocoumarins, the compounds behind grapefruit's drug interactions.

The research: A meta-analysis of grape seed extract found a small blood pressure drop and no clear effect on lipids or glucose^[23]. Grapefruit juice blocks the CYP3A4 enzyme in the gut and can raise blood levels of statins, some calcium channel blockers and other drugs^[24][25].

In Payarmin: Grape seed is second on the list, so possibly a meaningful share of the blend. The grapefruit amount is unknown and likely tiny; still, people on CYP3A4-sensitive drugs should mention it to a pharmacist.

The eight amino acids

L-Glutamine, L-Tyrosine, L-Arginine Base, Beta-Alanine, GABA, L-Ornithine HCL, L-Tryptophan, L-Carnitine Base

Amino acids and close relatives

These are building blocks or messengers the body already makes or gets from protein foods. Each has a separate story: glutamine for the gut and GLP-1, tyrosine for alertness, arginine for nitric oxide, beta-alanine for muscle buffering, GABA for calm, ornithine for ammonia handling, tryptophan for serotonin and carnitine for fat transport into mitochondria.

The research: Glutamine at 15 g raised GLP-1 and lowered post-meal glucose a little in type 2 diabetes^[26]. Beta-alanine is studied at 3.2 to 6.4 g a day for high-intensity exercise^[27]. The others are also gram-dose ingredients in research.

In Payarmin: Positions 14 to 22, the lighter half of a 200 mg blend. A single egg supplies hundreds of milligrams of most of these amino acids. Tryptophan, though small, is worth mentioning to anyone on an antidepressant.

Monoammonium glycyrrhizinate (licorice)

Monoammonium Glycyrrhizinate

Ammonium salt of glycyrrhizin, the sweet compound in licorice root

Glycyrrhizin is about 50 times sweeter than sugar and is used mainly as a sweetener and flavor masker, which is likely its role in a bitter herbal liquid.

The research: Regular, larger intakes of licorice raise blood pressure and lower potassium by blocking an enzyme that protects the kidney's mineral balance^[22][21].

In Payarmin: Eighteenth of 22, so very likely a few milligrams or less. Still, people with high blood pressure, heart or kidney disease, or on diuretics should be aware it is there.

The liquid base: glycerin, sweeteners, preservatives

The "other ingredients" line reads: glycerin, water, organic lemon extract, stevia extract 97% (Reb A), xylitol, sodium benzoate, potassium sorbate, citric acid and natural flavors. Glycerin is a sweet, thick solvent that carries plant extracts; stevia and xylitol add sweetness without much sugar; sodium benzoate and potassium sorbate prevent mold and bacteria once the bottle is opened; citric acid adjusts acidity.

Two points matter. Xylitol is safe for people in these amounts, but it is highly toxic to dogs, even in small quantities, so store the bottle where a pet cannot chew it. And glycerin, stevia and xylitol barely affect blood sugar at 1 to 2 mL, so the base itself will not spoil a glucose reading.

What the ingredient list adds up to

Read on its own, the list looks like a well-stocked metabolic formula: chromium, gymnema, green tea, ginseng, African mango, adaptogens and amino acids. Read with the amounts, it is a trace of chromium and a small spoon of many things. The ingredients with the best glucose evidence (chromium, gymnema, ginseng) are all present at doses far below what was studied.

That does not make Payarmin harmful, and the label is more complete than many. It does mean the honest expectation is "a light botanical routine", and that anyone serious about their numbers should judge it with a meter and keep the refund deadline in mind.

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